Droplet fate in indoor environments, or can we prevent the spread of infection?

Why Can We See a Local Spread of Chikungunya Virus (CHIKV) Infection?

Can We Prevent, Delay, or Shorten the Course of Dementia?

ou already know how it ends when you are born " , my mother said in sorrow after my father died. And she is not even medically qualifi ed. Should we extend this common wisdom on the realities of old age towards the development of dementia? In other words, is dementia a curse that is inescapably linked to old age? In a new study in PLoS Medicine , Carol Brayne and colleagues show that in a large...

Can we prevent, reduce or reverse intestinal fibrosis in IBD?

Intestinal fibrosis is a common complication of in inflammatory bowel disease (IBD) and can occur in both ulcerative colitis (UC) and Crohn's disease (CD), but is much more prevalent in CD. Fibrosis is a consequence of local chronic inflammation and is characterized by abnormal deposition of extracellular matrix (ECM) proteins producted by activated myofibroblasts. Current anti-inflammatory the...

Can we Prevent Onychomycosis?

Onychomycosis is a fungal infection involving the nail unit. Distal lateral subungal onychomycosis (DLSO) is the most common subtype and usually results from untreated tinea pedis. Once fungus has invaded the nail unit, it can be a challenge to treat. Though onychomycosis has been historically viewed as a cosmetic concern, treating this disease is important due to potential complications, espec...

Can we reduce the spread of HIV infection by suppressing herpes simplex virus type 2 infection?

Overwhelming evidence from observational epidemiological studies indicates that herpes simplex virus type 2 (HSV-2) infection enhances the risk of acquiring HIV infection. Studies of genital shedding of HIV have suggested that HSV-2 infection also increases the onward transmission of HIV-1 by HIV/HSV-2 co-infected patients. Several randomized controlled trials were initiated to assess the impac...